2012年11月19日 星期一

Study links breast cancer risk to plastics employment

Women who have worked for companies that make plastic injection molded parts for the automotive industry have a significantly higher risk of developing breast cancer than women who have not been exposed to that type of working environment, say a team of 12 researchers, whose work was funded by a number of Canadian groups, including Health Canada.

The report, published Nov. 19 in the Journal of Environmental Health, examined the occupational backgrounds of 1,006 women with breast cancer in the Ontario counties of Essex and Kent and compared them to a control group of 1,The oreck XL professional air purifier,146 women in the region who did not have breast cancer.

The report said that the breast cancer study group of 1,006 women included 26 women who worked in the plastics automotive sector. Based upon that group of 26 women, the report said women in the plastics automotive sector were almost five times more likely than women in the control group to develop breast cancer prior to menopause.

“One year in plastics (auto) employment is estimated to increase the odds of breast cancer by 9 percent,” said the report, with the cases of “excess breast cancer” largely “limited to small automotive parts suppliers, which would include some plastics operations.”

The report does not contain information directly linking the exposure of those 26 women to any particular chemical or identify any specific chemicals to which those women had been exposed on their jobs. It simply notes that the women in those environments are exposed to a wide number of chemicals that have been suspected of causing cancer.

The American Chemistry Council, based in Washington, took exception to that analysis.

“It is concerning [to us] that the authors could be over-interpreting their results and unnecessarily alarming workers,” ACC said in a statement issued on Nov. 19, after it had the opportunity to review the full study. “This study included no data showing if there was actual chemical exposure, from what chemicals, at what levels, and over what period of time [exposure might have occurred] in any particular workplace.”

“Although this is a worthy and important area of research,” ACC said, “it is inappropriate to use such research as the basis for speculation about causes of patterns of cancer rates among occupations without any information of substance about whether there are actual exposures, to what actual substances, and how big [those exposures] might be.”

John Heinze, a scientist who works for a non-profit research association in Washington, concurred.

“This is ... basically a survey of the jobs held by over 1,000 Canadian women who had breast cancer compared to an equal number of women who didn’t have breast cancer,” Heinze told Plastics News.

“Since the case and controls were supposedly matched on other health and demographic variables, any difference in breast cancer incidence was assumed [by the researchers] to be due to occupational exposure to carcinogens and endocrine disruptors,Posts with indoor tracking system on TRX Systems develops systems that locate and track personnel indoors.We recently added Stained glass mosaic Tile to our inventory.” he said.

“However,Our technology gives rtls systems developers the ability. occupational exposures were not measured, nor were questions asked specifically regarding occupational exposures,” said Heinze. “So the results ... only demonstrate statistical associations, not cause and effect. Without measurement of exposure levels, the statistical comparison of job histories between the two groups is not meaningful [and] the paper offers very little but speculation.Find detailed product information for howo spare parts and other products.”

The 12-person research team does not cite specific evidence or link the higher cancer rate among the automotive workers to any specific chemical exposure.

Instead, the report simply noted that a number of plastics used in plastic manufacturing have ‘identified’ as endocrine-disrupting chemicals and that there are a number of ways workers making plastic-injection molding parts can be exposed to ‘harmful’ chemicals.

“Many plastics have been found to release estrogenic chemicals [and] such additives as phthalates, and polybrominated diphenyl ethers have been identified as endocrine-disrupting chemicals,” said the report.

“Additionally, some of the monomers present in the manufacturing of polymers have been identified as mutagenic and/or carcinogenic [and] several monomers, additives, and related solvents, such as vinyl chloride, styrene, and acrylonitrile have been identified as mammary carcinogens in animal studies,” said the report. “Cumulative exposure to mixtures of various estrogenic chemicals may compound the effect.”

Similarly, the report did not delineate any specific ways the women in the study had been exposed to such chemicals. It simply pointed out how such workers could potentially be exposed to those chemicals.

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